PUBLICATIONS
JOURNAL ARTICLES
Development of innovative
biomedical materials
Development of novel biomaterials
Development of new chemical entities
Nanotheranostics generation, biosensors and tracking studies
JOURNAL ARTICLES 2024
State of the art in organometallic ruthenium metallodrugs for breast cancer treatment: Advances and innovations
Elena Domínguez-Jurado; Agustín Lara-Sánchez; Iván Bravo; Alberto Ocaña; Carlos Alonso-Moreno Coordination chemistry reviews, Vol 523, Part 1, 15 January 2025 https://doi.org/10.1016/j.ccr.2024.216252
Boron Complexes with Propiolamidinato Ligands: Synthesis, Structure, and Photophysical Properties
Blanca Parra-Cadenas, Iván Bravo, M. Consuelo Ripoll Lorente, Carlos Ginés, David Elorriaga, Fernando Carrillo-Hermosilla Inorg. Chem. 2024, 63, 26, 12120–12132 https://doi.org/10.1021/acs.inorgchem.4c01241
Antitumoral activity of a CDK12 inhibitor in colorectal cancer through a liposomal formulation
Fluorescence lifetime nanothermometer based on the equilibrium formation of anthracene AIE-excimers in living cells
Consuelo Ripoll, Almudena del Campo-Balguerías, Carlos Alonso-Moreno, Diego Herrera-Ochoa, Alberto Ocaña, Cristina Martín, Andrés Garzón-Ruíz, Iván Bravo Journal of Colloid and Interface Science; Volume 674 https://doi.org/10.1016/j.jcis.2024.06.157
A New Guanidine-Core Small-Molecule Compound as a Potential Antimicrobial Agent against Resistant Bacterial Strains
Noelia Morata-Moreno, Ramón Pérez-Tanoira, Almudena del Campo-Balguerias, Fernando Carrillo-Hermosilla, Marcos Hernando-Gozalo, Carlos Rescalvo-Casas, Ana V. Ocana, Pedro Segui, Carlos Alonso-Moreno, Francisco C. Pérez-Martínez, Milagros Molina-Alarcón...
Spectroscopic study on volasertib: Highly stable complexes with albumin and encapsulation into alginate/montmorillonite bionanocomposites
Jesús Fernández-Sainz, Diego Herrera-Ochoa, Pedro J. Pacheco-Liñán, Margarita Darder, José Albaladejo, Iván Bravo, Andrés Garzón-Ruiz Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; Volume 322 https://doi.org/10.1016/j.saa.2024.124823
Protein aggregation monitoring in cells under oxidative stress: a novel fluorescent probe based on a 7-azaindole-BODIPY derivative
Diego Herrera-Ochoa, Iván Llano, Consuelo Ripoll, Pierre Cybulski, Martin Kreuzer, Susana Rocha, Eva M. García-Frutos, Iván Bravo and Andrés Garzón-Ruiz July 2024; Journal of Materials; Chemistry B 12 (31) https://doi.org/10.1039/D4TB00567H
Sustainable farms from a biogenic CO2 source: The CO2 management pig slurry strategy
Abdessamad Gueddari; Ángela García-Alaminos; Carlos Alonso-Moreno; Jesús Canales-Vázquez; Santiago García-Yuste Chemical Engineering Journal 2024-07; Journal article https://doi.org/10.1016/j.cej.2024.152231
Monitoring cancer treatments in melanoma cells using a fluorescence lifetime nanoprobe based on a CdSe/ZnS quantum dot functionalized with a peptide containing D-penicillamine and histidine
Diego Herrera-Ochoa, Iván Bravo, Andrés Garzón-Ruiz Colloids and Surfaces B: Biointerfaces 2025-01; Journal article https://doi.org/10.1016/j.colsurfb.2024.114265
Chitosan-coated MIL-100(Fe) nanoparticles for enhanced piperine release in breast cancer treatment
Christian Rafael Quijia, Alberto Ocaña, Carlos Alonso‑Moreno, Regina Célia Galvão Frem, Marlus Chorilli. Journal of Molecular Structure, Volume 1305, 2024, https://doi.org/10.1016/j.molstruc.2024.137801
JOURNAL ARTICLES 2023
Minimizing sperm oxidative stress using nanotechnology for breeding programs in rams
Jurado-Campos A, Soria-Meneses PJ, Arenas-Moreira M, Alonso-Moreno C, Rodríguez-Robledo V, Soler AJ, Garde JJ, Del Rocío Fernández-Santos M. J Anim Sci Biotechnol. 2023 Aug 10;14(1):106 doi: 10.1186/s40104-023-00907-3.
Synthesis, characterization, and antibacterial activities of a heteroscorpionate derivative platinum complex against methicillin-resistant Staphylococcus aureus
Nam-Cha SH, Domínguez-Jurado E, Tinoco-Valencia SL, Pérez-Tanoira R, Morata-Moreno N, Alfaro-Ruiza R, Lara-Sánchez A, Esteban J, Luján R, Alonso-Moreno C, Seguí P, Ocaña A, Gónzalez ÁL, Aguilera-Correa JJ, Pérez-Martínez FC, Alarcón MM.Front Cell Infect Microbiol....
Unusually High Affinity of the PLK Inhibitors RO3280 and GSK461364 to HSA and Its Possible Pharmacokinetic Implications
Fernández-Sainz J, Pacheco-Liñán PJ, Ripoll C, González-Fuentes J, Albaladejo J, Bravo I, Garzón-Ruiz A. Unusually High Affinity of the PLK Inhibitors RO3280 and GSK461364 to HSA and Its Possible Pharmacokinetic ImplicationsMol Pharm. 2023 Mar...
Macrophage Cell Membrane Coating on Piperine-Loaded MIL-100(Fe) Nanoparticles for Breast Cancer Treatment
Quijia, C.R.; Navegante, G.; Sábio, R.M.; Valente, V.; Ocaña, A.; Alonso-Moreno, C.; Frem, R.C.G.; Chorilli, M. J. Funct. Biomater. 2023, 14, 319. https://doi.org/10.3390/jfb14060319.
Guanylation Reactions for the Rational Design of Cancer Therapeutic Agents
del Campo-Balguerías A, Parra-Cadenas B, Nieto-Jimenez C, Bravo I, Ripoll C, Poyatos-Racionero E, Gancarski P, Carrillo-Hermosilla F, Alonso-Moreno C, Ocaña A. International Journal of Molecular Sciences 2023; 24(18):13820. https://doi.org/10.3390/ijms241813820.
Formation of Highly Emissive Anthracene Excimers for Aggregation-Induced Emission/Self-Assembly Directed (Bio)imaging
Pacheco-Liñán PJ, Alonso-Moreno C, Ocaña A, Ripoll C, García-Gil E, Garzón-Ruíz A, Herrera-Ochoa D, Blas-Gómez S, Cohen B, Bravo I ACS Appl Mater Interfaces. 2023 Sep 27;15(38):44786-44795. doi: 10.1021/acsami.3c10823.
Unexpected luminescence of non-conjugated biomass-based polymers: new approach in photothermal imaging
de la Cruz-Martínez F, Bresolí-Obach R, Bravo I, Alonso-Moreno C, Hermida-Merino D, Hofkens J, Lara-Sánchez A, Castro-Osma JA, Martín C J Mater Chem B. 2023 Jan 4;11(2):316-324. PMID: 36353924. doi: 10.1039/d2tb02033e.
Anti-EGFR conjugated nanoparticles to deliver Alpelisib as targeted therapy for head and neck cancer
Juan, A.; Segrelles, C.; del Campo-Balguerías, A.; Bravo, I.; Silva, I.; Peral, J.; Ocaña, A.; Clemente-Casares, P.; Alonso-Moreno, C.; Lorz, C.https://doi.org/10.1186/s12645-023-00180-z
One-pot terpolymerization of CHO, CO2 and L-lactide using chloride indium catalysts
Marc Martínez de Sarasa Buchaca, Felipe de la Cruz Martínez, Luis F. Sánchez-Barba, Juan Tejeda, Ana M. Rodríguez, José A. Castro-Osma, Agustín Lara-Sánchez Dalton Trans. 2023, 52, 3482-3492. https://doi.org/10.1039/D3DT00391D
Enhanced Antitumoral Activity of Encapsulated BET Inhibitors When Combined with PARP Inhibitors for the Treatment of Triple-Negative Breast and Ovarian Cancers
Juan A, Noblejas-López MDM, Bravo I, Arenas-Moreira M, Blasco-Navarro C, Clemente-Casares P, Lara-Sánchez A, Pandiella A, Alonso-Moreno C, Ocaña A. Cancers (Basel). 2022 Sep 15;14(18):4474. PMID: 36139634; PMCID: PMC9496913. doi: 10.3390/cancers14184474.
JOURNAL ARTICLES 2022
Options to Improve the Action of PROTACs in Cancer: Development of Controlled Delivery Nanoparticles
Juan A, Del Mar Noblejas-López M, Arenas-Moreira M, Alonso-Moreno C, Ocaña A. Front Cell Dev Biol. 2022 Feb 3;9:805336. PMID: 35186955; PMCID: PMC8851355 doi: 10.3389/fcell.2021.805336.
Clinical considerations for the design of PROTACs in cancer
Nieto-Jiménez C, Morafraile EC, Alonso-Moreno C, Ocaña A. Mol Cancer. 2022 Mar 7;21(1):67. PMID: 35249548; PMCID: PMC8900451. https://doi.org/10.1186/s12943-022-01535-7
A bis(pyrazolyl)methane derivative against clinical Staphylococcus aureus strains isolated from otitis externa
Ocaña AV, Aguilera-Correa JJ, Domínguez-Jurado E, Pérez-Martínez FC, Pérez-Tanoira R, López-Carretero Y, Masiá-Mondejar J, Castro-Osma JA, Esteban J, Alonso-Moreno C, Molina-Alarcón M, Seguí P. Laryngoscope Investig Otolaryngol. 2022 Jan 18;7(1):283-290. doi:...
A Novel Quantum Dot-Based pH Probe for Long-Term Fluorescence Lifetime Imaging Microscopy Experiments in Living Cells
Herrera-Ochoa D, Pacheco-Liñán PJ, Bravo I, Garzón-Ruiz A. ACS Appl Mater Interfaces. 2022 Jan 19;14(2):2578-2586. https://doi.org/10.1021/acsami.1c19926
Characterization of Tuna Gelatin-Based Hydrogels as a Matrix for Drug Delivery
Hermida-Merino C, Cabaleiro D, Lugo L, Valcarcel J, Vázquez JA, Bravo I, Longo A, Salloum-Abou-Jaoude G, Solano E, Gracia-Fernández C, Piñeiro MM, Hermida-Merino D. Gels. 2022 Apr 12;8(4):237 doi: 10.3390/gels8040237.
Multifunctional PLA/Gelatin Bionanocomposites for Tailored Drug Delivery Systems
Moya-Lopez C, Juan A, Donizeti M, Valcarcel J, Vazquez JA, Solano E, Chapron D, Bourson P, Bravo I, Alonso-Moreno C, Clemente-Casares P, Gracia-Fernández C, Longo A, Salloum-Abou-Jaoude G, Ocaña A, Piñeiro MM, Hermida-Merino C, Hermida-Merino D. Pharmaceutics. 2022...
Polylactide Perspectives in Biomedicine: From Novel Synthesis to the Application Performance
Moya-Lopez C, González-Fuentes J, Bravo I, Chapron D, Bourson P, Alonso-Moreno C, Hermida-Merino D.Pharmaceutics. 2022 Aug 11;14(8):1673.https://doi.org/10.3390/pharmaceutics14081673
Enhanced Antitumoral Activity of Encapsulated BET Inhibitors When Combined with PARP Inhibitors for the Treatment of Triple-Negative Breast and Ovarian Cancers
Juan A, Noblejas-López MDM, Bravo I, Arenas-Moreira M, Blasco-Navarro C, Clemente-Casares P, Lara-Sánchez A, Pandiella A, Alonso-Moreno C, Ocaña A Cancers (Basel). 2022 Sep 15;14(18):4474. PMID: 36139634; PMCID: PMC9496913 doi: 10.3390/cancers14184474.
Vitamin E Lipid-Based Nanodevices as a Tool for Ovine Sperm Protection against Oxidative Stress: Impact on Sperm Motility
Jurado-Campos, A.; Soria-Meneses, P.J.; Arenas-Moreira, M.; Alonso-Moreno, C.; Bravo, I.; Rodríguez-Robledo, V.; Sánchez-Ajofrín, I.; Soler, A.J.; Garde, J.J.; Fernández-Santos, M.d.R. Antioxidants 2022, 11, 1988. https://doi.org/10.3390/antiox11101988.
Intramolecular charge transfer and molecular flexibility: Key parameters to be considered in the design of highly fluorescent p-phenylene vinylene derivatives
Pedro J. Pacheco-Liñán, Amparo Navarro, Juan Tolosa, Mónica Moral, Cristina Martín, Iván Bravo, Johan Hofkens, Joaquín C. García-Martínez, Andrés Garzón-Ruiz Dyes and Pigments, Volume 199, March 2022, 110105 https://doi.org/10.1016/j.dyepig.2022.110105
JOURNAL ARTICLES 2021
Tuning the Cytotoxicity of Bis-Phosphino-Amines Ruthenium(II) Para-Cymene Complexes for Clinical Development in Breast Cancer
Domínguez-Jurado E, Cimas FJ, Castro-Osma JA, Juan A, Lara-Sánchez A, Rodríguez-Diéguez A, Shafir A, Ocaña A, Alonso-Moreno CPharmaceutics. 2021 Sep 26;13(10):1559https://doi.org/10.3390/pharmaceutics13101559
Polyester Polymeric Nanoparticles as Platforms in the Development of Novel Nanomedicines for Cancer Treatment
Niza E, Ocaña A, Castro-Osma JA, Bravo I, Alonso-Moreno C. Cancers (Basel). 2021 Jul 6;13(14):3387. doi: 10.3390/cancers13143387.
Novel Fluorescence Guanidine Molecules for Selective Sulfate Anion Detection in Water Complex Samples over a Wide pH Range
Pacheco-Liñán PJ, Alonso-Moreno C, Carrillo-Hermosilla F, Garzón-Ruiz A, Martín C, Sáez C, Albaladejo J, Bravo I. ACS Sens. 2021 Sep 24;6(9):3224-3233 https://doi.org/10.1021/acssensors.1c00876
Mithramycin delivery systems to develop effective therapies in sarcomas
Estupiñán Ó, Niza E, Bravo I, Rey V, Tornín J, Gallego B, Clemente-Casares P, Moris F, Ocaña A, Blanco-Lorenzo V, Rodríguez-Santamaría M, Vallina-Álvarez A, González MV, Rodríguez A, Hermida-Merino D, Alonso-Moreno C, Rodríguez R. J Nanobiotechnology. 2021 Sep...
New titanocene derivative with improved stability and binding ability to albumin exhibits high anticancer activity
Serrano R, Martinez-Argudo I, Fernandez-Sanchez M, Pacheco-Liñan PJ, Bravo I, Cohen B, Calero R, Ruiz MJ. J Inorg Biochem. 2021 Oct; 223:111562. https://doi.org/10.1016/j.jinorgbio.2021.111562
Vitamin E Delivery Systems Increase Resistance to Oxidative Stress in Red Deer Sperm Cells: Hydrogel and Nanoemulsion Carriers
Jurado-Campos A, Soria-Meneses PJ, Sánchez-Rubio F, Niza E, Bravo I, Alonso-Moreno C, Arenas-Moreira M, García-Álvarez O, Soler AJ, Garde JJ, Fernández-Santos MDR Antioxidants (Basel). 2021 Nov 6;10(11):1780. PMID: 34829650; PMCID: PMC8615287. doi:...
Long-lived highly emissive MOFs as potential candidates for multiphotonic applications
Mario Gutiérrez, Cristina Martín, Johan Hofkens, Jin-Chong Tan Journal of Materials Chemistry C 9 (43), 15463-15469. https://doi.org/10.1039/D1TC03540A
“Concentration-in-Control” self-assembly concept at the liquid–solid interface challenged
Gangamallaiah Velpula, Cristina Martin, Brent Daelemans, Gunther Hennrich, Mark Van der Auweraer, Kunal S Mali, Steven De Feyter Chemical science, 2021, 12 (39), 13167-13176. https://doi.org/10.1039/D1SC02950A
Heteroscorpionate Rare-Earth Catalysts for the Low-Pressure Coupling Reaction of CO2 and Cyclohexene Oxide
Felipe de la Cruz-Martínez, Marc Martínez de Sarasa Buchaca, Juan Fernández-Baeza, Luis F Sánchez-Barba, Ana M Rodríguez, Carlos Alonso-Moreno, José A Castro-Osma, Agustín Lara-Sánchez Organometallics, 2021, 40 (10), 1503-1514....
The Effect of WS2 Nanosheets on the Non-Isothermal Cold- and Melt-Crystallization Kinetics of Poly(l-lactic acid) Nanocomposites
Mohammed Naffakh, Pablo Rica, Carmen Moya-Lopez, José Antonio Castro-Osma, Carlos Alonso-Moreno, Diego A Moreno Polymers, 2021, 13 (13), 2214. https://doi.org/10.3390/polym13132214
JOURNAL ARTICLES 2020
Assessment of doxorubicin delivery devices based on tailored bare polycaprolactone against glioblastoma
Niza E, Castro-Osma JA, Posadas I, Alonso-Moreno C, Bravo I, Garzón A, Canales-Vázquez J, Ceña V, Lara-Sánchez A, Albaladejo J, Otero A. Pharm. 2019 Mar 10;558:110-119. Epub 2019 Jan 9. PMID: 30639216 doi: 10.1016/j.ijpharm.2018.12.079.
PEI-coated PLA nanoparticles to enhance the antimicrobial activity of carvacrol
Niza E, Božik M, Bravo I, Clemente-Casares P, Lara-Sanchez A, Juan A, Klouček P, Alonso-Moreno C. Food Chem. 2020 Oct 30;328:127131. Epub 2020 May 23. PMID: 32485586. doi: 10.1016/j.foodchem.2020.127131.
Functionalized CdSe/ZnS Quantum Dots for Intracellular pH Measurements by Fluorescence Lifetime Imaging Microscopy
Pacheco-Liñán PJ, Bravo I, Nueda ML, Albaladejo J, Garzón-Ruiz A. ACS Sens. 2020 Jul 24;5(7):2106-2117. https://doi.org/10.1021/acssensors.0c00719
Antibody Conjugation of Nanoparticles as Therapeutics for Breast Cancer Treatment
Juan A, Cimas FJ, Bravo I, Pandiella A, Ocaña A, Alonso-Moreno C. Therapeutics for Breast Cancer Treatment. Int J Mol Sci. 2020 Aug 21;21(17):6018. PMID: 32825618; PMCID: PMC7504566. doi: 10.3390/ijms21176018.
An Overview of Antibody Conjugated Polymeric Nanoparticles for Breast Cancer Therapy
Juan A, Cimas FJ, Bravo I, Pandiella A, Ocaña A, Alonso-Moreno C. Pharmaceutics. 2020 Aug 25;12(9):802. PMID: 32854255; PMCID: PMC7558516. doi: 10.3390/pharmaceutics12090802.
Controlled Delivery of BET-PROTACs: In Vitro Evaluation of MZ1-Loaded Polymeric Antibody Conjugated Nanoparticles in Breast Cancer
Cimas FJ, Niza E, Juan A, Noblejas-López MDM, Bravo I, Lara-Sanchez A, Alonso-Moreno C, Ocaña A. Pharmaceutics. 2020 Oct 19;12(10):986. PMID: 33086530; PMCID: PMC7589709 doi: 10.3390/pharmaceutics12100986.
Synthesis and photophysical studies of an indigo derivative: N-octyl-7,7′-diazaindigo
Gustavo de Miguel, Andrés Garzón-Ruiz, Amparo Navarro, Eva M. García-Frutos RSC Adv., 2020,10, 42014-42020. https://doi.org/10.1039/D0RA06451C
Unraveling the photophysical and semiconducting properties of color converter luminogens with aggregation induced emission characteristics
Paz Fernández-Liencres, Mónica Moral, Zhang Yilin, Ting Han, Meijuan Jiang, Andrés Garzón-Ruiz, Amparo Navarro, Kam Sing Wongc and Ben Zhong Tang Mater. Chem. C, 2020,8, 16757-16768. https://doi.org/10.1039/D0TC03632C
Design and Synthesis of Annulated Benzothiadiazoles via Dithiolate Formation for Ambipolar Organic Semiconductors
Matthew A. Kolaczkowski, Andrés Garzón-Ruiz, Akash Patel, Zhiyuan Zhao, Yunlong Guo, Amparo Navarro, and Yi Liu ACS Appl. Mater. Interfaces 2020, 12, 47, 53328–53341. https://doi.org/10.1021/acsami.0c16056
Shedding Light on the Origin of Solid-State Luminescence Enhancement in Butterfly Molecules
Antonio Sánchez-Ruiz, Julián Rodríguez-López, Andrés Garzón-Ruiz, Sonia B. Jiménez-Pulido, Nuria A. Illán-Cabeza, Amparo Navarro, Joaquín C. García-Martínez Chemistry A European Journal, 26, 61, 2020, 13990-14001. https://doi.org/10.1002/chem.202002920
JOURNAL ARTICLES 2019
Screening and Preliminary Biochemical and Biological Studies of [RuCl(p-cymene)(N,N-bis(diphenylphosphino)-isopropylamine)][BF4] in Breast Cancer Models
Corrales Sánchez V, Nieto-Jiménez C, Castro-Osma JA, de Andrés F, Pacheco-Liñán PJ, Bravo I, Rodríguez Fariñas N, Niza E, Domínguez-Jurado E, Lara-Sánchez A, Ríos Á, Gómez Juárez M, Montero JC, Pandiella A, Shafir A, Alonso-Moreno C, Ocaña A. ACS Omega. 2019 Aug...
Poly(Cyclohexene Phthalate) Nanoparticles for Controlled Dasatinib Delivery in Breast Cancer Therapy
Niza E, Nieto-Jiménez C, Noblejas-López MDM, Bravo I, Castro-Osma JA, Cruz-Martínez F, Buchaca MMS, Posadas I, Canales-Vázquez J, Lara-Sanchez A, Hermida-Merino D, Solano E, Ocaña A, Alonso-Moreno C. Nanomaterials (Basel). 2019 Aug 27;9(9):1208. PMID: 31461998; PMCID:...