Development of new chemical entities
(2018-2025)
Phenyl-guanidine derivatives as potential therapeutic agents for glioblastoma multiforme: catalytic syntheses, cytotoxic effects and DNA affinity
RSC Advances, 2016, volumen 6, páginas 8267-8274
https://doi.org/10.1039/C5RA17920C
Aminophosphine ligands as a privileged platform for development of antitumoral ruthenium(ii) arene complexes
L. M. Broomfield, C. Alonso-Moreno, E. Martin, A. Shafir, I. Posadas, V. Ceña y J. A. Castro-Osma
Dalton Transactions, 2017, volumen 46, páginas 16113-16122
https://doi.org/10.1039/C7DT03369A
Synthesis, characterization, DNA interactions and antiproliferative activity on glioblastoma of iminopyridine platinum(II) chelate complexes
I. Posadas, C. Alonso-Moreno, I. Bravo, F. Carrillo-Hermosilla, A. Garzón, J. M. Martínez, A. M. Rodríguez, J. Fernández-Baeza, A. Otero
Journal of Inorganic Biochemistry, 2017, 168, 46-54
https://doi.org/10.1016/j.jinorgbio.2016.11.032
Conjugation with carbon nanotubes improves the performance of mesoporous silicon as Li-ion battery anode
Ana M. Rodríguez Fernández-Pacheco, Carlos Alonso-Moreno, Iván Bravo Pérez, José Antonio Castro Osma, Juan Fernández Baeza, Juan Manuel Martínez Martínez, Antonio Otero
https://doi.org/10.1038/s41598-020-62564-0
Alternating Copolymerization of Epoxides and Anhydrides Catalyzed by Aluminum Complexes
ACS Omega 2018
https://doi.org/10.1021/acsomega.8b02759
State of the art in organometallic ruthenium metallodrugs for breast cancer treatment: Advances and innovations
Coordination chemistry reviews, Vol 523, Part 1, 15 January 2025
https://doi.org/10.1016/j.ccr.2024.216252
Tuning the Cytotoxicity of Bis-Phosphino-Amines Ruthenium(II) Para-Cymene Complexes for Clinical Development in Breast Cancer
Domínguez-Jurado E, Cimas FJ, Castro-Osma JA, Juan A, Lara-Sánchez A, Rodríguez-Diéguez A, Shafir A, Ocaña A, Alonso-Moreno C
Pharmaceutics. 2021 Sep 26;13(10):1559
https://doi.org/10.3390/pharmaceutics13101559
Clinical considerations for the design of PROTACs in cancer
Mol Cancer. 2022 Mar 7;21(1):67. PMID: 35249548; PMCID: PMC8900451.
https://doi.org/10.1186/s12943-022-01535-7
A bis(pyrazolyl)methane derivative against clinical Staphylococcus aureus strains isolated from otitis externa
Laryngoscope Investig Otolaryngol. 2022 Jan 18;7(1):283-290.
doi: 10.1002/lio2.722
Synthesis, characterization, and antibacterial activities of a heteroscorpionate derivative platinum complex against methicillin-resistant Staphylococcus aureus
Nam-Cha SH, Domínguez-Jurado E, Tinoco-Valencia SL, Pérez-Tanoira R, Morata-Moreno N, Alfaro-Ruiza R, Lara-Sánchez A, Esteban J, Luján R, Alonso-Moreno C, Seguí P, Ocaña A, Gónzalez ÁL, Aguilera-Correa JJ, Pérez-Martínez FC, Alarcón MM.
Front Cell Infect Microbiol. 2023 Mar 27;13:1100947
https://doi.org/10.3389/fcimb.2023.1100947
Guanylation Reactions for the Rational Design of Cancer Therapeutic Agents
International Journal of Molecular Sciences 2023; 24(18):13820.
https://doi.org/10.3390/ijms241813820.
Evaluation of Heteroscorpionate Ligands as Scaffolds for the Generation of Ruthenium(Ii) Metallodrugs in Breast Cancer Therapy
Domínguez-Jurado E, Ripoll C, Lara-Sánchez A, Ocaña A, Vitórica-Yrezábal IJ, Bravo I, Alonso-Moreno C.
J Inorg Biochem. 2024 Apr;253:112486.
https://doi.org/10.3389/fcimb.2023.1100947